 
 
    |  |  | |||||||
|  | 2013 |  | 2012 | |||||
| Conversion of convertible debt to common stock |  | $ | 523,927 |  |  | $ | 924,904 |  | 
| Preferred dividends paid by issuance of stock |  |  |  |  |  |  | 82,500 |  | 
| Business combination: |  |  |  |  |  |  |  |  | 
| Issuance of Series E liability |  |  |  |  |  |  | 18,955,742 |  | 
| Issuance of contingent consideration |  |  |  |  |  |  | 11,109,020 |  | 
| Issuance of replacement warrants |  |  |  |  |  |  | 1,883,751 |  | 
| Common stock issued in satisfaction of subscription receivable |  |  |  |  |  |  | 2,790,107 |  | 
| Effect of cancellation of escrowed shares |  |  |  |  |  |  | 195,132 |  | 
| Obligation to issue shares for professional services |  |  |  |  |  |  | 30,000 |  | 
| Effect of modification of convertible debt |  |  | 151,032 |  |  |  |  |  | 
| Common Stock issued for committed equity financing facility |  |  | 204,015 |  |  |  |  |  | 
| Warrants issued for term loan modification |  |  | 151,758 |  |  |  |  |  | 
| Warrants issued for term loan |  |  | 568,324 |  |  |  |  |  | 
| Common stock and warrants issued for release of security interest in patents |  |  | 325,693 |  |  |  |  |  | 
| Warrants issued in connection with convertible debt |  |  | 1,353,842 |  |  |  |  |  | 
| Derivative liability for embedded conversion option |  |  | 965,484 |  |  |  |  |  | 
| Common stock issued for professional services |  |  | 17,850 |  |  |  |  |  | 
| Common stock issued for settlement of contingency |  |  | 39,150 |  |  |  |  |  |