| Component: (Network and Table) | |
|---|---|
| Network | 00400 - Statement - Statements of Cash Flows (http://www.nivalis.com/role/StatementStatementsOfCashFlows)  | 
| Table | (Implied) | 
| Reporting Entity [Axis] | 0001626199 (http://www.sec.gov/CIK) | 
| Statements of Cash Flows | Period [Axis] | ||
|---|---|---|---|
2016-01-01 - 2016-12-31  | 2015-01-01 - 2015-12-31  | 2014-01-01 - 2014-12-31  | |
Statements of Cash Flows  | |||
Operating activities  | |||
Net loss  | (  | (  | (  | 
Adjustments to reconcile net loss to net cash used in operating activities:  | |||
Depreciation and loss on disposal of assets  | |||
Stock-based compensation expense  | |||
Change in value of preferred stock warrant liabilities and derivative  | (  | ||
Amortization of deferred financing costs and noncash interest  | |||
Changes in operating assets and liabilities:  | |||
Prepaid expenses and other  | (  | (  | |
Accounts payable  | |||
Accrued direct program expenses  | |||
Accrued employee benefits  | (  | ||
Accrued other liabilities  | (  | (  | |
Net cash used in operating activities  | (  | (  | (  | 
Investing activities  | |||
Purchases of property and equipment  | (  | (  | (  | 
Purchases of marketable securities  | (  | (  | |
Proceeds from maturities and sales of marketable securities  | |||
Net cash provided by (used in) investing activities  | (  | (  | |
Financing activities  | |||
Proceeds from issuance of common stock, net of offering costs  | |||
Proceeds from issuance of common stock under employee share plans  | |||
Proceeds from issuance of convertible preferred stock, net  | |||
Decrease in restricted cash  | |||
Proceeds from notes payable, net  | |||
Principal payment on debt  | (  | ||
Net cash provided by financing activities  | |||
Net increase (decrease) in cash and cash equivalents  | (  | (  | |
Cash and cash equivalents, beginning of period  | 24,991,000    | ||
Cash and cash equivalents, end of period  | 24,203,000    | 24,991,000    | 27,812,000    | 
Supplemental disclosures of cash flow information  | |||
Cash paid for interest  | |||
Conversion of convertible preferred stock to common stock  | |||
Conversion of convertible debt and accrued interest to convertible preferred stock, net  | 24,655,000    | ||