Property and equipment, net consisted of the following (in thousands):

 

 

 

 

 

 

 

 

 

 

December 31, 

 

 

    

2016

    

2015

 

Manufacturing equipment

 

$

3,748

 

$

3,748

 

Laboratory equipment

 

 

15,021

 

 

13,681

 

Computer and office equipment

 

 

2,553

 

 

3,596

 

Furniture and fixtures

 

 

2,078

 

 

2,062

 

Software

 

 

12,945

 

 

12,715

 

Construction in process

 

 

814

 

 

375

 

Leased vehicles

 

 

7,058

 

 

3,039

 

Leasehold improvements

 

 

38,513

 

 

38,465

 

 

 

 

82,730

 

 

77,681

 

Less accumulated depreciation and amortization

 

 

(62,218)

 

 

(56,606)

 

 

 

$

20,512

 

$

21,075