Property, plant and equipment consist of the following at December 31, 2016 and 2015, in thousands:

 

 

 

At December 31,

 

 

 

2016

 

 

2015

 

Laboratory equipment

 

$

37,303

 

 

$

33,558

 

Computer equipment and software

 

 

9,650

 

 

 

5,732

 

Furniture and fixtures

 

 

6,002

 

 

 

2,906

 

Leasehold improvements

 

 

45,362

 

 

 

35,825

 

Land

 

 

9,080

 

 

 

 

Construction in progress

 

 

68,182

 

 

 

1,285

 

 

 

 

175,579

 

 

 

79,306

 

Less: accumulated depreciation

 

 

(61,007

)

 

 

(51,494

)

 

 

$

114,572

 

 

$

27,812